Question

Angiopoietin-like 4 role in hematopoietic stem cells

Answer 1

Hematopoietic stem cells (HSCs) can be found in bone marrow, peripheral blood, and umbilical cord blood, and are important in studies of blood disorders and blood-related malignancies. We provide a comprehensive set of tools for isolation, expansion, differentiation, and characterization of HSCs and their derivatives.

CD34 is a common marker for identifying human HSCs, and we offer a serum-free medium for CD34+ cells, as well as methods to isolate CD34+ cells from blood or bone marrow.

Answer 2

Answer:

$\bf{\huge{\mathfrak{\boxed{\red{Answer\:}}}}}$

The angiopoietin family of growth factors is composed of four members that bind to the Tie-2 tyrosine kinase receptor and are important modulators of angiogenesis18. The Tie-2–Ang1 signaling pathway also has a crucial role in maintaining HSCs in a quiescent state in the bone marrow niche24.

$\mathcal{thnku :)}$