Angiotensin I is converted into angiotensin II by angiotensin convertase enzyme (ACE) secreted by
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Answer: It is located mainly in the capillaries of the lungs but can also be found in endothelial and kidney epithelial cells.
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Angiotensin-converting enzyme (EC 3.4.15.1), or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasoconstrictor angiotensin II. Therefore, ACE indirectly increases blood pressure by causing blood vessels to constrict. ACE inhibitors are widely used as pharmaceutical drugs for treatment of cardiovascular diseases.[5]
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