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It has recently become possible to “weigh” DNA molecules by measuring the influence of their mass on a nano-oscillator. FIGURE shows a thin rectangular cantilever etched out of silicon (density 2300 kg/m3 ) with a small gold dot at the end. If pulled down and released, the end of the cantilever vibrates with simple harmonic motion, moving up and down like a diving board after a jump. When bathed with DNA molecules whose ends have been modified to bind with gold, one or more molecules may attach to the gold dot. The addition of their mass causes a very slight—but measurable—decrease in the oscillation frequency.
it has recently become possible to “weigh” DNA molecules by measuring the influence of their mass on a “nano-oscillator,” a thin rectangular cantilever etched out of silicon with a small gold dot at the end.If pulled down and released the end of the cantilever vibrates with simple harmonic motion, moving up and down like a diving board.DNA molecules can attach to the gold dot, and the addition of their mass causes a very slight decrease in the oscillation frequency.