Antabuse reaction severe nausea and vomitting what are the medicinal aid
Answers
Answer:
Explanation:
Some individuals should never take disulfiram, and others should use extra caution when taking the drug. Do not take disulfiram if you have a nickel allergy, a sulfur allergy or a hypersensitivity to disulfiram or other derivatives of thiuram, which are commonly found in rubber.
Patients with the following conditions or circumstances should be cautious when taking disulfiram:
PSYCHOSIS
Patients with a history of psychosis should take disulfiram only when they’re stable.
SEVERE MYOCARDIAL DISEASE OR CORONARY OCCLUSION
Disulfiram should be used only when the risk of alcohol consumption outweighs the risk of interactions with these conditions.
PREGNANCY
The risk to the baby is unknown, and inpatient rehab is a preferred treatment approach over disulfiram for pregnant women with alcohol use problems.
Women who are nursing should not take disulfiram. Mothers can take the prescription drug once they discontinue nursing.
Disulfiram may interact with several medications, disrupting their effectiveness or causing adverse events.
Medications known to interact with disulfiram include:
Coumadin (warfarin)
Dilantin (phenytoin)
Elavil (amitriptyline)
Flagyl (metronidazole)
Isoniazid
Librium (chlordiazepoxide)
Norpramin (desipramine)
Rifadin (rifampin)
Theophylline
Tofranil (imipramine)
Tricyclic antidepressants
Valium (diazepam)
Before taking disulfiram, patients should tell their health provider if they heave heart disease, kidney disease, thyroid problems, epilepsy, liver disease, diabetes or a history of mental health concerns.
Who Should Take Disulfiram?
Disulfiram should never be taken by individuals under the influence of alcohol. The side effects of the interaction between alcohol and disulfiram are the same regardless of which substance is consumed first. That’s why disulfiram is prescribed only to people who have maintained at least 12 hours of sobriety.
Other candidates for disulfiram include those who are:
Motivated and committed to sobriety
Aware of the consequences of drinking while taking disulfiram
Open to taking it with supervision
Free of conditions or medications contraindicated by the drug
Doctors educate patients about the risks of mixing alcohol with disulfiram before prescribing the drug. They may perform a breathalyzer test, physical exam or a pregnancy test to ensure disulfiram use is safe. Health providers may not require supervised consumption of disulfiram, but many doctors and therapists strongly recommend supervised treatment to encourage compliance.
Most people begin with a 250 mg dose taken once a day for one to two weeks. The smallest known effective dose is 125 mg, and the maximum dose per day is 500 mg. If patients miss a dose, they should take it as soon as they remember unless it’s almost time for the next dose. They should never take a double dose of the medication.
The drug is available only in tablet form in the United States. It can be swallowed or crushed and consumed with water, milk, tea, coffee, fruit juice or a soft drink.