Antibacterial effects of quaternary bis-phosphonium and ammonium salts of pyridoxine on staphylococcus aureus cells: a single base hitting two distinct targets?
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We studied the effects of quaternary bis-phosphonium and bis-ammonium salts of pyridoxine with lipophilic substituents on the survival and morphology of Staphylococcus aureus cells. We found that, while originating from the same base, they exhibit considerably different antimicrobial mechanisms.
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