Question

Antifungal drugs binds to
in fungal membrane
causing membrane to
become leaky​

Answer 1

Explanation:

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These drugs interact with sterols in cell membranes (ergosterol in fungal cells; cholesterol in human cells) to form channels through the membrane, causing the cells to become leaky (Fig. 76-2). The polyene antifungal agents include nystatin, amphotericin B, and pimaricin.