antigen lysis and polyclonal response_?
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antigen lysis and polyclonal response_?
Lysis: Some powerful antibodies attack plasma membrane of the cell and thereby cause rupture of plasma membrane.
Antibodies are synthesised by B lymphocytes and exist in 2 forms- either membrane bound or secreted. B-lymphocytes use membrane bound antibody to interact with antigens. Each antigen sensitized B-cell makes antibodies all of the same specificity i.e. One which is able to react with the same antigenic determinants. Its progeny (as a consequence of mitotic division) is referred to as a clone. The clone will continue making antibody of the same specificity. Simultaneously, there will be lots of other clones of different specificity. This is known as a polyclonal response.
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