Are amides activating or deactivating?
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Alkoxy, amide, ester groups less strongly activating. Alkyl Groups – (with no electron withdrawing groups). ... Atoms with pi-bonds to electronegative groups – Strongly deactivating
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Explanation:
Overreaction of Aniline
The strongest activating and ortho/para-directing substituents are the amino (-NH2) and hydroxyl (-OH) groups. ... Because of their high nucleophilic reactivity, aniline and phenol undergo substitution reactions with iodine, a halogen that is normally unreactive with benzene derivatives.
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