* are formed in sickle cell anaemia
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abnormal hemoglobin causes red blood cells to become rigid, sticky and misshapen.
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Sickle cell disease/anemia Sickle cell disease is a genetic disorder caused by abnormal genes inherited from one parent. Normal red blood cells (RBCs) are biconcave disc-shaped and flow easily in blood vessels, but in sickle cell disease, the red blood cells are crescent-shaped.
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