as per the ip the ph of purified water is
Answers
Answer:
USP Standards For Purified Water
pH 5.0 to 7.0
Chloride (mg/l) 0.5
Sulfate (mg/l) 1.0
Ammonia (mg/l) 0.03
Calcium (mg/l) 1.0
Answer:
Specifies 4 grades of water with resistivity of >18, >4, >1, >0.2 Mohm.cm and TOC of <50, <50, <200 ppb with each grade subdivided into 4 categories depending on microbial counts and endotoxin levels.
Explanation:
In addition to being an ingredient in many pharmaceutical products, purified water is also used to cleanse production equipment. It is therefore of utmost significance. The Indian Pharmacopeia, British Pharmacopeia, and United States Pharmacopeia all provide specifications for purified water. Purified water used in the production of pharmaceuticals must meet these requirements.
Sr. No. PARAMETERS LIMITS
1 Description Clear, Colourless, odourless and tasteless liquid.
2 pH Between 5.0 to 7.0
3 Conductivity: Not more than 1µS/Cm
4 Acidity / Alkalinity: On addition of Methyl red solution the resulting solution should be not red. On addition of Bromo thymol blue solution the resulting solution should be not blue.
5 Ammonium: Test solution should not be coloured in intense with compared to standard solution.
6 Calcium & magnesium: A Pure blue coloured should be produced.
7 Heavy Metals: Not more than 0.1ppm
8 Chloride: The appearance of the solution should not be changed for at least 15 minutes.
9 Nitrate: Not more than 0.2 ppm
10 Sulphate:The appearance of the solution should not be changed for at least 1 hour.
11 Oxidisable substances: The test solution should remain faintly pink.
12 Residue on evaporation: Not more than 0.001%
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