Question

ASSERTION : Phenlypyruvic acid is excreted through urine in case of phenylketonuria .
REASON : The affected individual lacks enzyme phenylalanine hydroxylase.

Answer 1

Both assertion and reason are true and reason is the correct explanation of assertion.
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Phenylketonuria is an inherited error of metabolism cause by deficiency in the enzyme phenylalanine hydroxylase.
It is an autosomal recessive trait.
It is a hereditary human condition resulting from the inability to convert phenylalanine into tyrosine .
This leads to over production of phenylalanine and it's conversion to phenlypyruvic acid and other derivatives .
These are the excreted in urine due to poor absorption by kidneys.
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