Chemistry, asked by Prateek1000, 11 months ago

Asymmetric hydrogenation and asymmetric transfer hydrogenation

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Answered by TojoRealMadrid
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Asymmetric hydrogenation is a chemical reaction that adds two atoms of hydrogen preferentially to one of two faces of an unsaturated substrate molecule, such as an alkene or ketone. The selectivity derives from the manner that the substrate binds to the chiral catalysts. In jargon, this binding transmits spatial information (what chemists refer to as chirality) from the catalyst to the target, favoring the product as a single enantiomer. This enzyme-like selectivity is particularly applied to bioactive products such as pharmaceutical agents and agrochemicals.

Hydrogen transfer reduction processes are attracting increasing interest from synthetic chemists in view of their operational simplicity and high selectivity. In this tutorial review the most significant advances recently achieved in the stereoselective reduction of unsaturated …

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Answered by jeevankishorbabu9985
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Asymmetric hydrogenation

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