At high altitude, the,
(A) number of RBC increases
(C) number of RBC decreases
(B) size of RBC increases
(D) size of RBC decreases
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Explanation:
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At high altitudes, there is a decrease in oxygen hemoglobin saturation. This hypoxic condition causes hypoxia-inducible factor 1 (HIF- 1) to become stable and stimulates the production of erythropoietin (EPO), a hormone secreted by the kidneys. EPO stimulates red blood cell production from bone marrow in order to increase hemoglobin saturation and oxygen delivery. Thus, the total number of RBC increases.
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- The term "anemia" is a general term that refers to a decrease in red blood cells. Anemia can occur from either a decrease in the number of red blood cells, a decrease in the hemoglobin content, or both. Red blood cells live for approximately four months in the bloodstream.
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