(b) Explain why DNA replication cannot proceed to the regions of the chromosome labeled as I in Figure 1B unless topoisomerase binds ahead of each advancing replication fork in region II.
Answers
Answer:
full form of DNA is deoxyrebonucleic acid
Explanation:
hope it help full
Answer:
Because replication only follows single strands, not double strands, of DNA. As you can see in the figure, the regions of the chromosome marked as I are on a double strand of DNA and replication proceeds only in regions of single strands of DNA. Topoisomerase, is the enzyme responsible for binding the double strand of DNA and separating each strand, forming two single strands, before the replication bubble arrives, only then can replication continue. For this reason, we can say that in the region of the chromosome marked as I, it will be necessary for the topoisomer to separate each strand of DNA for replication to proceed.
Explanation:
DNA replication cannot proceed because of its Y-shaped structure, this active region is called a replication fork.
Topoisomerase are enzymes that participate in the unwinding of DNA. The winding problem of DNA arises due to the intertwined nature of its double-helical structure. During DNA replication and transcription, DNA becomes overwound ahead of a replication fork.DNA replication will then proceed. Replication fork is the area where the replication of DNA will actually take place.