Question

(b) In 1992, the BHC Company developed a new method from the starting materials isobutyl benzene and acetic anhydride through a Friedel-Crafts acylation, carbonyl reduction, chloride substitution, and Grignard reaction. i) Write the synthesis showing all the reactant atoms that are incorporated into the desired product, and the atoms of the desired product in green, and all other atoms in brown. ii) Set up a table of atom economy for this synthesis analogous to table. iii) Calculate the % atom economy of this synthesis.

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Answer 1

Answer:

In 1992, the BHC Company developed a new method from the starting materials isobutyl benzene and acetic anhydride through a Friedel-Crafts acylation, carbonyl reduction, chloride substitution, and Grignard reaction. i) Write the synthesis showing all the reactant atoms that are incorporated into the desired product, and the atoms of the desired product in green, and all other atoms in brown. ii) Set up a table of atom economy for this synthesis analogous to table. iii) Calculate the % atom economy of this synthesis.