Question

(b) The objectives of a study by van Vollenhoven et al.
(A-10) were to examine the effectiveness of
etanercept alone and etanercept in combination with
methotrexate in the treatment of rheumatoid
arthritis. The researchers conducted a retrospective
study using data from the STURE database, which
collects efficacy and safety data for all patients
starting biological treatments at the major hospitals
in Stockholm, Sweden. The researchers identified 40
subjects who were prescribed etanercept only and 57
subjects who were given etanercept with
methotrexate. Using a 100-mm visual analogue scale
(the higher the value, the greater the pain),
researchers found that after 3 months of treatment,
the mean pain score was 36.4 with a
dard error
of the mean of 5.5 for subjects taking etanercept
only. In the sample receiving etanercept plus
methotrexate, the mean score was 30.5 with a
standard error of the mean of 4.6.
Construct the suitable confidence limits. U
al
of confidence as 99%.​

Answer 1

Answer:

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