Question

Barbituric acid derivatives activity as tranquilizers

Answer 1

Barbituric acid was first synthesized in 1864 and has no pharmacological activity but barbital derived frombarbituric acid has sedative hypnotic property. ... Barbiturates are central nervous system depressants and are used medically as sedatives, hypnotics, anaesthetics as well as anticonvulsants.

Answer 2

A barbiturate[a] is a drug that acts as a central nervous system depressant, and can therefore produce a wide spectrum of effects, from mild sedation to death. Barbiturates are effective as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential.