Question

Beta oxidation regulation and disorder

Answer 1

Answer:

Explanation:t

Fatty acid oxidation is the mitochondrial aerobic process of breaking down a fatty acid into acetyl-CoA units. Fatty acids move in this pathway as CoA derivatives utilizing NAD and FAD.

Fatty acids are activated before oxidation, utilizing ATP in the presence of CoA-SH and acyl-CoA synthetase. Long-chain acyl-CoA enters mitochondria bound to carnitine. Inside mitochondria beta oxidation of fatty acids takes place in which two carbon atoms are removed in the form of acetyl-CoA from acyl-CoA at the carboxyl terminal. The bond is broken between the second carbon/beta carbon and the third carbon/gamma carbon, hence the name beta oxidation. This process provides energy from fats.