between What is the ditterence Gaelles disease (Myxoedemo 2 and Grove's disease &
Answers
Answer:
In this latter sense, myxedema refers to deposition of mucopolysaccharides in the dermis, which results in swelling of the affected area. One manifestation of myxedema occurring in the lower limb is pretibial myxedema, a hallmark of Graves disease, an autoimmune form of hyperthyroidism
Explanation:
plz Mark me brainliest☺
Answer:
Explanation:
Graves' disease includes thyrotoxicosis, goiter, exophthalmos, and pretibial myxedema when fully expressed, but can occur with one or more of these features.
Graves' disease is a disease of "autoimmunity", but the final cause of autoimmunity remains unclear. A strong hereditary tendency is present. Inheritance of HLA antigens DR3, DQ 2, and DQA1*0501 predispose to Graves' disease. The abnormal immune response is characterized by the presence of antibodies directed against thyroid tissue antigens, including antibodies that react with the thyrotrophin receptor by binding to the receptor. Some of these antibodies act as agonists and stimulate the thyroid. The best-known of the antibodies is the serum factor first reported as "LATS", now known as "TSAb".It has been reported in active Graves' disease that T- lymphocyte suppressor cell function is diminished and suppressor cell number is reduced. It is hypothesized that an abnormality in the control of autoimmune responses is present in this disease and leads to production of high levels of autoantibodies that may stimulate the thyroid or eventually cause thyroid damage and cell death.
please mark me as brilliant