Question

binding of oxygen with haemoglobin is primarily related to partial pressure of oxygen.how?​

Answer 1

Answer:

yes. binding of oxygen with heamoglobin is primary related to partial pressure of oxygen

Explanation:

as the partial pressure of oxygen increases the more oxygen binds to the hemoglobin

Answer 2

Answer:

Partial Pressure is the most pivotal factor that determines how much oxygen binds to hemoglobin is termed partial pressure of Oxygen.

The higher the partial pressure of Oxygen, the more oxygen combines with Haemoglobin or Hb.

Explanation: When reduced hemoglobin is completely converted to oxyhemoglobin or Hb-O2, then the hemoglobin is said to be fully saturated. The average saturation of hemoglobin with oxygen is expressed by the Percent saturation of hemoglobin.

For example, if each hemoglobin molecule has bound to 2 oxygen molecules, then the hemoglobin is 50 % saturated because each Hb can bind a maximum of 4 Oxygen molecules.

1. Oxygen-haemoglobin dissociation curve illustrates the relationship between the percent saturation of hemoglobin and partial pressure of oxygen.
2. When the partial pressure of oxygen is high, hemoglobin binds with large amounts of oxygen molecules until all the available hemoglobin molecules are saturated (100% saturation of hemoglobin).

• The partial pressure of Oxygen is higher in pulmonary capillaries and a lot of oxygen binds to hemoglobin.

    3. When the partial pressure of Oxygen is low, hemoglobin is only  

        partially saturated.

• The partial pressure of oxygen is lower in tissue capillaries and hemoglobin does not hold as much oxygen, and the dissolved Oxygen is unloaded via diffusion into the tissue cells.

There is a diagram attached below showing the relationship between hemoglobin saturation and Partial pressure of Oxygen at normal body temperature in the form of an Oxygen-hemoglobin dissociation curve.

• In the diagram, one can see that hemoglobin is 75% saturated with Oxygen at 40mmHg, this is the average partial pressure of tissue cells in a person at rest. Therefore only 25% of available oxygen unloads from the hemoglobin and is used by tissue cells under resting conditions.