Biology
Integrins bind to extracellular matrix proteins because
The extracellular matrix proteins have cadherins.
O The extracellular matrix proteins contain RGD sequences.
O The cytoskeletal proteins are highly glycosylated.
O The integrins contain RGD sequences
O The extracellular matrix proteins are highly glycosylated
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Integrins are the principal receptors used by animal cells to bind to the extracellular matrix. They are heterodimers and function as transmembrane linkers between the extracellular matrix and the actin cytoskeleton. A cell can regulate the adhesive activity of its integrins from within.
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