Both overproduction and underproduction of growth hormone leads to disorders in the body.Explain
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I.I Lack of Growth Hormone
The growth hormone deficiency can be caused by defects in the anterior pituitary (hyposecretory) or secondary hypothalamic dysfunction (GHRH deficiency) .1 As a result of these hormonal deficiencies in childhood, dwarfism. Its main picture is a short stature due to bone growth retardation. Supporting images include: muscle growth disorders due to decreased muscle protein synthesis, low fat subtype mobilization. Child growth does not fit into the right age range, for example: when 10 years old, has a height that should be owned by a 5 year old child.
Other known types of disorders are larvae of larvae (larvae dwarfism) .1.2 In this disorder, the illustration shown in patients is similar to those with growth hormone deficiency. However, in the larvae of this larva, the rate of growth hormone in the blood is as normal as normal. The larvae of the larvae as discussed above are due to the sensitivity of growth hormone receptors so that the effects of these hormones are not achieved optimally. In addition, these larvae have other types which are caused by somatomedin deficiency.
Dwarfism is associated with puberty which affects the secretion of gonadotropin hormones.2 If the growth hormone deficiency is severe, the patient may experience puberty. However, growth hormone concentrations are below physiological levels of puberty. The lack of growth hormone in adults (after the epiphyte plate closes) experiences some disorders such as: decreased muscle strength as well as decreased bone density.
I.II The Advantages of Growth Hormone
Hormone growth hormones are most often caused by tumors on somatotrophs. 1In the case of children, the main symptom is high striking (more than 2 meters is gigantism). This height increases significantly without interfering with the proportion of the body. The advantages of this hormone also lead to enlarged muscles and other tissues grow larger than normal capacity. Therefore, the therapy given to these gigantic patients is the removal of the tumor on the somatotrof (the main) and the administration of somatostatin (supplements).
The growth hormone deficiency can be caused by defects in the anterior pituitary (hyposecretory) or secondary hypothalamic dysfunction (GHRH deficiency) .1 As a result of these hormonal deficiencies in childhood, dwarfism. Its main picture is a short stature due to bone growth retardation. Supporting images include: muscle growth disorders due to decreased muscle protein synthesis, low fat subtype mobilization. Child growth does not fit into the right age range, for example: when 10 years old, has a height that should be owned by a 5 year old child.
Other known types of disorders are larvae of larvae (larvae dwarfism) .1.2 In this disorder, the illustration shown in patients is similar to those with growth hormone deficiency. However, in the larvae of this larva, the rate of growth hormone in the blood is as normal as normal. The larvae of the larvae as discussed above are due to the sensitivity of growth hormone receptors so that the effects of these hormones are not achieved optimally. In addition, these larvae have other types which are caused by somatomedin deficiency.
Dwarfism is associated with puberty which affects the secretion of gonadotropin hormones.2 If the growth hormone deficiency is severe, the patient may experience puberty. However, growth hormone concentrations are below physiological levels of puberty. The lack of growth hormone in adults (after the epiphyte plate closes) experiences some disorders such as: decreased muscle strength as well as decreased bone density.
I.II The Advantages of Growth Hormone
Hormone growth hormones are most often caused by tumors on somatotrophs. 1In the case of children, the main symptom is high striking (more than 2 meters is gigantism). This height increases significantly without interfering with the proportion of the body. The advantages of this hormone also lead to enlarged muscles and other tissues grow larger than normal capacity. Therefore, the therapy given to these gigantic patients is the removal of the tumor on the somatotrof (the main) and the administration of somatostatin (supplements).
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Explanation:
Growth hormone released by pituitary is responsible for growth f the body. Its over production results in the excess growth and the disorder is called as 'Gigantism".
Whereas its underproduction results in underdevelopment of the growth and its disorder is known as 'Dwarfism".
Hence, both overproduction and underproduction of growth hormone leads to disorders in the body
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