Briefly mention the mechanism of action of FSH
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• FSH shows its effect by binding to its specific receptors present on the ovarian cell membrane. Binding of FSH to its specific receptor present over the cell surface activates an enzyme called adenylate cyclase. The biochemical responses then lead to physiological responses like overian growth.
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answer: A molecule of FSH binds on the receptor protein present on the cell surface and forms the hormone-receptor complex.
Formation of hormone-receptor complex activates the enzyme adenyl cyclase.
Adenyl cyclase converts ATP into cyclic AMP (cAMP) as a second messenger.
cAMP activates the follicular cells of membrane granulose to secrete estrogens.
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