can anyone pls give a report on a case of any people affected by stone man syndrome pls
Answers
Step-by-step explanation:
Fibrodysplasia ossificans progressiva (FOP) is a rare hereditary connective tissue disease characterized by the progressive ectopic ossification of ligaments, tendons, and facial and skeletal muscles throughout life. Symptoms begin in childhood as localized soft tissue swellings. Immobility and articular dysfunction appear with involvement of the spine and proximal extremities. The temporomandibular joint (TMJ) is a critical component involved in the maxillofacial region, resulting in severe limitation of masticatory function, although TMJ involvement is rare. The aim of this article is to present a 28-year-old man with dental problems and slowly progressive limitation of motion in the jaw, knees, shoulders and hips as well as neck distortion.
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Dr Zakir Ali Shah at the Department of Trauma and Orthopedic, Rashid Hospital, Dubai, United Arab Emirates and colleagues have reported a rare case of stone man syndrome. The case has appeared in the Journal of Medical Case Reports.
Stone man syndrome or Fibrodysplasia ossificans progressiva is a very rare autosomal dominant disorder and disabling syndrome characterized by postnatal progressive heterotopic ossification of the connective tissue and congenital malformation of the big toes. Fibrodysplasia ossificans progressiva has a worldwide prevalence of about 1 in 2 million births. Nearly 90% of patients with fibrodysplasia ossificans progressiva are misdiagnosed and mismanaged and thus undergo unnecessary interventions. So far, the number of reported existing cases worldwide is about 700.
According to history a 10-year-old Pakistani boy presented to our clinic in Pakistan with a 6-month history of pain and tender masses on the back, left arm, and left hip. The pain was insidious in onset and gradually worsened, causing difficulty in walking and decreased range of motion of shoulders and hips.
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