can gastric juice of humans digest?
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Interestingly, we found that NAs are digested efficiently by human gastric juice. By performing digests with commercial, recombinant and mutant pepsin, a protein-specific enzyme, we learned that the digestion of NAs could be attributed to pepsin rather than to the acidity of the stomach.
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ᴡᴇ ғᴏᴜɴᴅ ᴛʜᴀᴛ ʜᴜᴍᴀɴ ɢᴀsᴛʀɪᴄ ᴊᴜɪᴄᴇ ᴡᴀs ᴀʙʟᴇ ᴛᴏ sɪɢɴɪғɪᴄᴀɴᴛʟʏ ᴅɪɢᴇsᴛ ɪɴɢᴇsᴛᴇᴅ ɴᴀs ɪɴ ᴠɪᴛʀᴏ. ғᴜʀᴛʜᴇʀ sᴛᴜᴅʏ ᴅᴇᴍᴏɴsᴛʀᴀᴛᴇᴅ ᴛʜᴀᴛ ᴛʜᴇ ᴅᴏᴍɪɴᴀɴᴛ ᴇɴᴢʏᴍᴇ ɪɴ ɢᴀsᴛʀɪᴄ ᴊᴜɪᴄᴇ, ᴘᴇᴘsɪɴ, ᴡᴀs ʀᴇsᴘᴏɴsɪʙʟᴇ ғᴏʀ ᴛʜɪs ᴀᴄᴛɪᴠɪᴛʏ.
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