can water be used for extraction of alkaloids from cinchona give reason
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Explanation:
You can extract in methanol. Take the extract and partition between dichloromethane (DCM)and acidic water (you can use HCl to make the water acidic). Set the DCM extract aside in case you are interested in neutral and acidic compounds).Next, make the water basic (you may use ammonia to make the water basic), and extract again with DCM. The alkaloids will be in the DCM layer as the free-base.
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Explanation:
Quinine is extracted from the ground product obtained from the alkaline maceration of cinchona bark by treating it with a solvent mixture of at least one hydrocarbon and a chlorinated hydrocarbon, ketone or alcohol.
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