Question

Can we make a substance to reach it in absolute zero

Answer 1

Absolute zero cannot be achieved, although it is possible to reach temperatures close to it through the use of cryocoolers, dilution refrigerators, and nuclear adiabatic demagnetization. The use of laser cooling has produced temperatures less than a billionth of a kelvin.

Answer 2

practically it is not possible because all molecular motion stops at absolute zero temperature