Question

can we use wolff krishner reaction for compound which react with base?

if no then why​

Answer 1

Because the Wolff–Kishner reduction requires highly basic conditions, it is unsuitable for base-sensitive substrates. In some cases, formation of the required hydrazone will not occur at sterically hindered carbonyl groups, preventing the reaction.

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Answer 2

Because the Wolff–Kishner reduction requires highly basic conditions, it is unsuitable for base-sensitive substrates.

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