Can you distinguish a pair of enantiomers by IR- spectroscopy?
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For IR, enantiomers would have the same spectra, but diastereomers would have different spectra.
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The IR spectra of of the (R,R) and (S,S) enantiomers are identical. However, the VCD spectra have opposite sign (see the illustration at the top of the next page). Thus, computed VCD spectra can easily distinguish enantiomers
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