Cancer researchers must be experts in cell biology a discipline that includes cells of the immune system
Answers
Explanation:
Cancer Research
Leads the nation’s research efforts to improve cancer prevention, detection, diagnosis, and survivorship
Supports 71 NCI-Designated Cancer Centers and more than 5,000 grantees
Coordinates and supports all phases of clinical trials across 2,500 clinical trial sites nationwide, seeking the development of new and improved cancer treatments
Supports intramural research scientists in our own laboratories and clinics
Partners with industry, private philanthropic organizations, other federal agencies, and other national and foreign institutions to engage in cancer research and training opportunities that otherwise might not be possible because of their complexity and cost
Collaborates with private-sector life sciences companies to advance promising innovative technologies that fuel improvements in detection, diagnosis, and treatment of cancer
Supports the Frederick National Laboratory for Cancer Research, the only federally funded research and development center dedicated exclusively to biomedical research
Maintains long-term storage of publicly available cancer genomic and clinical data
Supports construction of laboratories, clinics, and related facilities for cancer research
Answer:To understand the molecular and cell biology of childhood cancers and leukemias and the interactions of malignant cells with host cells, especially those of the immune system and the tumor microenvironment
To understand the physiology and biology of vascular disease in hemoglobinopathies and to develop multimodal biophysical markers
To translate this knowledge into improvements in diagnosis, risk assessment, and therapy
Genomic and epigenomic abnormalities associated with malignancy
The interaction of cancer cells with the immune system and other cells in the tumor microenvironment
New therapeutic strategies targeting tumor cell abnormalities
The immune system
The TME along with companion biomarkers
The Institute’s Hematology research focuses on hemoglobinopathies, particularly sickle cell disease. The research calibrates biomarkers reflecting 1) cardiac autonomic nervous system imbalance and peripheral and pain-triggered vasoconstriction; and 2) peripheral vascular function and regional cerebral flow and oxygenation. This will provide standardized measurement and processing tools for clinical application.Neuroblastoma: New Approaches to Neuroblastoma Consortium
Leukemia: Therapeutic Advances for Childhood Leukemia/Lymphoma