Chemistry, asked by snehalprints, 6 months ago

carbonyl carbon atom is susceptible to attack by a nucleophile. Justify​

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Answered by ssheetalsingh8962
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Chemistry

Aldehydes, Ketones and Carboxylic Acids

Chemical Reactions of Aldehydes and Ketones

Among the given compounds, ...

CHEMISTRY

Among the given compounds, the most susceptible to nucleophilic attack at the carbonyl group is:

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This concept is related to nucleophilic addition reaction.

Rate of attack of nucleophile increases as the deficiency of carbonyl carbon increases.

In acetyl chloride [CH

3

COCl]due to presence of Cl group carbonyl carbon is become more deficient due negative inductive effect of Cl group, because of larger size of Cl, resonance interaction does not occur between Cl and carbonyl carbon ,so the electronegativity of Cl plays a role and nucleophilic addition occurs more easily.

Order of nucleophillic addition = acyl chloride >acid anhydride> carboxylic acid >ester>amide

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