Cases of Haemophilia A are reported in Queen Victoria's family,
Pedigree of Queen Victoria's family (Fig. 22.28) indicates that Queen
Victoria was a carrier mother, because she gave birth to an affected
at the other
SOL
Prince Leopold. Prince Leopold passed on this recessive X - linked to
in typical zigzag fashion through his carrier daughter (III – 1) to his
grandson Rupert (IV – 1). Assign genotype to each individual. probability their first child would suffer from heamophilia
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The family pedigree of Queen Victoria shows a number of hemophilic descendants because hemophilia is sex-linked recessive disorder and Queen Victoria was a carrier. X-linked recessive or sex-linked recessive disease most often occurs in males because Males have only one X chromosome. A single recessive gene on that X chromosome will cause the disease. Females have two X chromosomes so they can act as carriers for the disease. Hemophilia is a bleeding disorder that slows the blood clotting process.
So, the correct answer is 'Haemophilia is sex-linked recessive disorder and Queen Victoria was a carrier'.
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