Question

catabolism of purine synthesis? 5 marks​

Answer 1

Answer:

Purine Catabolism. The end product of purine catabolism in man is uric acid. Other mammals have the enzyme urate oxidase and excrete the more soluble allantoin as the end product. ... Uric acid is formed primarily in the liver and excreted by the kidney into the urine

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Answer 2

1) The end product of purine catabolism in man is uric acid.

2) The purine bases guanine and hypoxanthine are converted to xanthine and then to uric acid, which is excreted from the body.

3) The end-point of this pathway in humans is unusual.

4) Other mammals have the enzyme urate oxidase and excrete the more soluble allantoin as the end product.

5) Nucleic acids are constantly being degraded and resynthesized. Purine and pyrimidine bases which are not degraded are recycled.