cell junction is mediated by integrin
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Alternatively, cell junctions can be categorised into two main types according to what interacts with the cell: cell–cell junctions, mainly mediated by cadherins, and cell–matrix junctions, mainly mediated by integrins.
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Cell junctions is divided into 2 types:
- those who link cells along, additionally referred to as animate thing junctions (tight, gap, adherens, and desmosomal junctions) and people that link cells to the living thing matrix (focal contacts/adhesion plaques and hemidesmosomes).
- These junctions play a distinguished role in maintaining the integrity of tissues in cellular organisms and a few, if not all of them, are concerned in signal transduction .
- Intercellular junctions and hemidesmosomes were initial known in tissues examined by microscopy.
- In distinction, the focal contact was initial determined in refined cells within the microscope by a method referred to as interference reflection.
- This procedure discovered specific sites wherever cells closely adhere to their substrate .
- These were referred to as focal contacts or adhesion plaques.
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