Cells that need more NADPH than they need Ribose 5 phosphate.
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When the cell needs NADPH more than it needs ribose 5-phosphate the cell will first carry out the oxidative phase then the non-oxidative phase and finally gluconeogenesis. This will help the cell recycle back the ribose 5-phosphate into glucose 6-phosphate which can be used to synthesize even more NADPH moelcules.
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