Centrifugal granulation pelletization techniques
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Pelletization can be defined as an agglomeration (size-enlargment) process that converts fine pow- ders or particles of bulk drugs and excipients into small, free-flowing, more or less spherical units, called pellets (7).
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Pellet (or bead) technology allows a variety of different drug delivery profiles to be achieved by coating a 'core' of drug and excipient with various polymers. ... The core is coated with a polymer. This process provides a very tight size distribution of pellets. Drug potencies up to 60% are possible...
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