Chain lengthening and shortening of aldos reaction with mechanism
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Glucose chain shortening and lengthening is the chemical processes for decreasing or increasing the carbon chain length of glucose. Glucose can be shortened by oxidation and decarboxylation to generate arabinose, a reaction known as the Ruff degradation.[1] To increase the glucose carbon chain, a series of chemical reactions can be used to add one more carbon at the aldehyde end of glucose; this process is known as the Kiliani–Fischer synthesis.[2]Fig 1: Glucose chain shortening and lengthening
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