Question

change the voice of the beginning 'Those.....'(We must empower those most vulnerable of social changes)​

Answer 1

Those most vulnerable of social changes must empowered by us.
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Answer 2

Those most vulnerable of social changes must be empowered.

The given sentence is written in active voice but the answer is in passive voice.

When in active voice, the agent (we) becomes very important, but in passive voice, the action, and the predicate part (those most vulnerable of social changes) becomes important.

So in any case there is this constant distinction that is made as part of the sentence.