Chapter 17 Narcotic Analgesics Multiple choice (Please choose the best option) 1. Analgesics are characterized by A. have analgesic and antipyretic effects B. have analgesic and anti-inflammatory effects C. have analgesic, antipyretic and anti-inflammatory effects D. have strong analgesic effect, no addiction E. have a strong analgesic effect, repeated use is easy to addiction 2. The effects of morphine on the central nervous system are A. Analgesia, sedation, hypnosis, respiratory depression B. Analgesia, sedation, cough, vomiting C. Analgesia, sedation, cough, respiratory excitement D. Analgesia, sedation, antiemetic and respiratory depression E. Analgesia, sedation, pupil dilation, respiratory depression 3. Opioid receptor antagonist is A. Dihydroetorphine B. Naloxone C. Fentanyl D. Pethidine E. Rotundine Essay questions 1. Describe the mechanism of morphine used in cardiogenic asthma, a cute pulmonary edema Chapter 18 Central Stimulants Multiple choice (Please choose the best option) 1.Clinically used for mild depression and bed-wetting A. Caffeine B. Ritalin C. Nikethamide D. Bemegride E. Dimefline 2. Which drug is mainly used to rescue toxication of sedative-hypnotics A. Nikethamide B. Dimefline C. Lobeline D. Bemegride E. Pemoline 3. Clinical use of pemoline includes EXCEPT: A. ADHD B. narcolepsy C. sextual dysfunction D. Mild depression E. Infantile bed-wetting Essay questions 1. Briefly describe the classification and representative drugs of central stimulants
Answers
Explanation:
Extraction of teeth has been a common, routine dental procedure done in clinics which may lead to moderate to severe pain postoperatively. Any pain postoperatively may cause a discomfort in particpants and affects their routine lifestyle. Preemptive analgesics plays an important role in reducing postoperative pain and distress associated with painful dental procedures. Nonsteroidal anti-inflammatory drugs are one of the treatment options to be used as pain relief for surgical teeth extraction. Wherelse, another commonly prescribed drug over-the-counter is Paracetamol. The purpose of this study is to evaluate the analgesic effect of both the drug as an preemptive analgesia. This study is a double blind , clinical trial. Twenty particpants were randomised into two group. Group A receiving Paracetamol (500mg) and Group B receiving Diclofenac (100mg) orally, 30 minute before the extraction is done. The pain intensity and the duration of the analgesia is evaluated using the Visual Analog Scale (VAS). Patient who were given Diclofenac (100mg) show a higher analgesic effect compare to Paracetamol (500mg).However, the analgesic effect in patient received Diclofenac is much more longer then patient received Paracetemol. Two different drug has been used in this study to evaluate their efficacy as an preemptive analgesic and it can be concluded that Diclofenac is more effective then Paracetamol as an preemptive analgesia.
Keywords
Dental Pain; Diclofenac; Extraction; Paracetamol; Preemptive Analgesia
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Thenarasu V, Gurunathan D, Selvarasu K. Comparison of Efficacy of Diclofenac And Paracetamol as Preemptive Analgesic Agent. Biomed Pharmacol J 2018;11(3).
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Thenarasu V, Gurunathan D, Selvarasu K. Comparison of Efficacy of Diclofenac And Paracetamol as Preemptive Analgesic Agent. Biomed Pharmacol J 2018;11(3). Available from: