chargaff's rule in detail plz explain
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Answer:
Chargaff's rules state that DNA from any cell of any organism should have a 1:1 stoichiometric ratio (base pair rule) of pyrimidine and purine bases and, more specifically, that the amount of guanine should be equal to cytosine and the amount of adenine should be equal to thymine.
Chargaff's rules state that DNA from any cell of any organism should have a 1:1 stoichiometric ratio of pyrimidine and purine bases and, more specifically, that the amount of guanine should be equal to cytosine and the amount of adenine should be equal to thymine. This pattern is found in both strands of the DNA.
According to chargaff's rule:-
1. Here adenine residues =120, cytosine residues = 120.
2. there fore total number of nucleotides = [A] + [T]+ [C]+[G] =120 X 4 = 480.
3. In humans, there is approximately 30% adenine.
4. According to Chargaff's rule, [A]+[G]=[C]+[T]
According to Chargaff's rule, [A]+[G]=[C]+[T]Here [A]=30% therefore % of [T] is also 30%.
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