chestnut compound was discovered by?
Answers
Answer:
The chestnuts are the deciduous trees and shrubs in the genus Castanea,
Answer:
The European chestnut is used by many communities around in the world in their traditional medicines.
The researchers also demonstrated how the extract works, by inhibiting the ability of MRSA bacteria to communicate with one another, a process known as quorum sensing.
In the new study, they isolated a novel active triterpenoid, named castaneroxy A, from the plant extract.
Tests on mouse skin infected with MRSA confirmed the molecule’s efficacy at shutting down the bacteria’s virulence, enabling the skin to heal more rapidly.
The scientists also characterized the crystal shape of castaneroxy A.
Understanding the 3D configuration of the crystal is important for future studies to refine and optimize the molecule as a potential therapeutic.
“We’re laying the groundwork for new strategies to fight bacterial infections at the clinical level,” Dr. Quave said.
“Instead of being overly concerned about treating the pathogen, we’re focusing on ways to better treat the patient.”
“Our goal is not to kill the microbes but to find ways to weaken them so that the immune system or antibiotics are better able to clear out an infection.”
A paper on the findings was published in the journal Frontiers in Pharmacology.
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