Question

Clinical features of liver disease in preeclampsia

Answer 1

Affected pregnant women typically present with nonspecific symptoms of weight gain, right upper quadrant pain (90%), nausea or vomiting (50%), or nonspecific viral‐like illness. Jaundice is seen in 40% of patients. Concomitant signs and symptoms of preeclampsia may or may not be present. Severe right upper‐abdominal pain may herald impending hepatic rupture. Other causes of right upper‐quadrant pain must be sought such as acute cholecystitis, acute pancreatitis, peptic ulcer disease, and acute fatty liver disease of pregnancy. Pregnant women with preeclampsia/HELLP may present with involvement of other organs, resulting in cerebral or visual symptoms, pulmonary edema, and renal insufficiency.