Question

Combination of amitriptyline and bupropion for fibromyalgia

Answer 1

It's unclear which neurotransmitters are affected by gabapentin or pregabalin. Both drugs improve pain, sleep, fatigue, and the quality of life in people with fibromyalgia to about the same degree as amitriptyline. ... Both drugs can also cause swelling, so people with heart failure should not take them.