Compare the prophase of mitosis and meiosis I
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Prophase in Mitosis
Mitosis occurs after interphase in eukaryotes. During interphase, the DNA is replicated, along with the organelles necessary to divide. This includes the centrosome, within which the centriole gets replicated. With a replicated genome and organelles, the cell can begin mitosis. The first stage of mitosis is prophase, and it sets the stage for the later stages of mitosis. During interphase preceding mitosis, the chromosomes exist in a loose state. At the onset of prophase, proteins associated with the DNA are activated, and the DNA winds around them and bundles in dense shapes. Under a microscope, this stage can be seen as a darkening of different places in the nucleus.
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Thus, when meiosis starts, there are two copies of each chromosome, attached as sister chromatids in the same chromosome. During prophase I, the chromosomes condense, as in mitosis. ... Unlike in mitosis, the sister chromosomes stay together through meiosis I, but the homologous chromosomes are separated.
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