Consider the following reaction
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Question :
Find product C in the given reaction
CH3-OH+ PBr3→A
A+ Alc.KCN →B
B +H3O+ →C
First Learn some rections : you
1) Preparation of Alkyl halide from alcohol .
R-OH + HCL/anhydrous ZnCl2→R-Cl
R-OH + PBr3 →R-Br
R-OH + SOCl2 →R-Cl
and other methods also .
2) SN² reaction
- It is second order reaction.
- Take peace in one step through transition state
- Tends proceed with strong nucleophile.
- Inversion of configuration take place.
⇒Example :
CH3-Cl + KCN→CH3-CN
3) Hydrolysis of Cynaides
⇒Example :
Benzonitrile + H3O+ → Benzoic acid
→Note if Hydrolysis is partial
product is Different in the above reaction
Solution :
first part reaction is reaction of alcohol with PBr3 : reaction as follows ,
CH3-OH + PBr3 → CH3-Br (A )
Second part of reaction :
Reaction of Alkyl halide with alc.KCN
it follows SN² reaction :
CH3-Br + alc. KCN → CH3-CN (B)
Last part of reaction :
Hydrolysis of Cynaides, reaction as follows
CH3-CN + H3O→ CH3-COOH (c)
_____________________________
Final product C = Ethanoic acid
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