Consider the lac operon of
e. Coli. When neither glucose nor lactose is present in the growth medium
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when neither glucose nor lactose is present in the growth medium the repressor is bound to the lac operator.
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f both glucose and lactose are both present, lactose binds to the repressor and prevents it from binding to the operator region. ... If, however, glucose is absent and lactose becomes the only available carbon source, the picture changes. Lactose still prevents the repressor from binding to the operator region.
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