Conversion of primary amine into secondary amine
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To preserve the nucleophilicity of amino compounds during conjugative radioiodination, a new method for converting primary amines to phenolic secondary amines was developed. ... The irreversible attachment of formylphenol to the amino group was accomplished by reduction of the imine with sodium cyanoborohydride.
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To preserve the nucleophilicity of amino compounds during conjugative radioiodination, a new method for converting primary amines to phenolic secondary amines was developed. ... The irreversible attachment of formylphenol to the amino group was accomplished by reduction of the imine with sodium cyanoborohydride.
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