create a metabolic pathway that begin with palmitoyl coA in mitochondrial matrix , and end up pyruvate yu have oxoloacetate, citrate shuttling , ATP , and erythrose 4 phosphate if you need them . (explain in 1000word )
Answers
Answer:Noncarbohydrate precursors of glucose are first converted into pyruvate or enter the pathway at later intermediates such as oxaloacetate and dihydroxyacetone phosphate (Figure 16.24). ... Lactate is readily converted into pyruvate by the action of lactate dehydrogenase (Section 16.1.
Explanation:
The transport of pyruvate into the mitochondria is via the transport protein pyruvate translocase. Pyruvate translocase transports pyruvate in a symport fashion with a proton, and hence is active, consuming energy. Upon entry to the mitochondria, the pyruvate is decarboxylated, producing acetyl-CoA.
In the presence of oxygen, pyruvate is converted to acetyl-CoA and then enters the citric acid cycle. More ATP can be formed from the breakdown of glucose when oxygen is present.
In humans, the most important metabolic pathways are: glycolysis - glucose oxidation in order to obtain ATP. citric acid cycle (Krebs' cycle) - acetyl-CoA oxidation in order to obtain GTP and valuable intermediates. oxidative phosphorylation - disposal of the electrons released by glycolysis and citric acid cycle.