Crucial role of the pentose phosphate pathway in malignant tumors
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The PPP serves a pivotal role in supporting cancer cell survival and growth by generating pentose phosphate for nucleic acid synthesis and providing nicotinamide-adenine dinucleotide phosphate (NADPH), which is needed for fatty acid synthesis and cell survival under stress conditions (7).
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The PPP serves a pivotal role in supporting cancer cell survival and growth by generating pentose phosphate for nucleic acid synthesis and providing nicotinamide-adenine dinucleotide phosphate (NADPH), which is needed for fatty acid synthesis and cell survival under stress conditions (7).
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