cyclic chain of reaction called tricarboxylic acid cycle is operated in
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The citric acid cycle (CAC) – also known as the TCA cycle (tricarboxylic acid cycle) or the Krebs cycle – is a series of chemical reactions to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins.
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The cyclic chain of reaction called tricarboxylic acid cycle is operated in the matrix of intracellular structures called mitochondria.
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- The Krebs cycle refers to the reactions that aid in the conversion of pyruvic acid to carbon dioxide and water in mitochondria. The citric acid cycle, or tricarboxylic acid cycle, is another name for it (TCA cycle).
- Acetyl CoA interacts with oxaloacetic acid to create citric acid in the first step of the citric acid cycle. Citric acid synthetase catalyses this process. Three carboxylic acid groups can be found in citric acid. In the presence of aconitase, citric acid is dehydrated to create cis-aconitic acid.
- By adding a molecule of water, the enzyme aconitase catalyses the synthesis of isocitric acid from cis-aconitic acid. Three carboxylic acid groups are found in citric acid, cis-aconitic acid, and isocitric acid. Ketoglutaric acid is formed via oxidative decarboxylation of isocitric acid. This is a catalysed reaction.
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